04/24/2014

The picture of the girl that you see is of 10 year old Colby Curtin, who was suffering from vascular cancer

By Live Dr - Sun Jun 21, 2:41 pm

Would we ever find an answer to the existence of vascular cancer? Lets see if we are able to throw some light on vascular cancer. The smooth muscle cells are cancerous, in fact, even more prone to cancer if they turn to be dividing cells. After all, vascular system is the body’s blood vessel network.

The picture of the girl that you see is of 10 year old Colby Curtin, who was suffering from vascular cancer. She had a simple wish of watching animated movie “Up” before dying which was fulfilled by Pixar. From sources it has been found out that a family friend contacted Pixar on which a studio employee visited Colby family with a DVD copy of the movie “Up”. Colby’s mother had no idea what was going on, all she could realize and think was that her daughter was moving Up, up to heaven. Very natural, as no mother can see her child diminish in front of her own eyes, saddening, in fact. On one hand we cannot stop appreciating Pixar for this kind and generous gesture towards the dying 3 year old child, while, on the other hand, the heartbreaking incident of the dying girl is surely striking our senses that the vascular cancer disease is increasing at a fast rate.

The reasons behind the growth of this disease could be smoking, hypertension, high cholesterol level, diabetes, getting quite prevalent amongst people over 50 years of age, who are obese, or from families having history of vascular diseases, stroke, heart attack.

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Wellington,  (DPA) A 30-year-old New Zealand woman was reported to be critically ill with swine flu Friday as the health ministry officially accepted that the disease had spread so widely that it could not contain it.
The patient was the first New Zealander to be put into intensive care with the illness. She was admitted Thursday evening to Wellington Hospital, and officials said she was morbidly obese and had a history of respiratory problems.

The ministry said that New Zealand had 216 confirmed cases of influenza H1N1, up 63 cases overnight, and 158 of them were current. Most people recovered from the infection without need for hospitalization or medical care, officials said.

They said they were moving from a policy of trying to contain the disease to managing it, reflecting the increased spread of the virus rather than a change in severity, especially in three main cities, Wellington, Christchurch and Auckland.

Victims were being encouraged to look after themselves at home. The anti-viral medication Tamiflu, which was previously given to all patients, would now only be dispensed to the seriously ill.

“The shift in New Zealand’s response is in keeping with the World Health Organization’s assessment that the overall severity of the disease is moderate but spreading globally,” a ministry statement said.

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  1. ETIOLOGICAL FACTORS
    1.AGE-risk increase with age
    2.Hormonal Influences-older age at menopause Increases Risk,number of pregnancies= high number is protective,age at first pregnancy =If greater than 30 doubles the risk compared to just greater than 20.
    3.BREAST FEEDING IS PROTECTIVE
    4.Oral contraceptive pills, High Oestrogen pill increases risk when used before the age of 20
    5.HORMONE replacement theraphy-women under 50 years are at no risk
    6.Oophorectomy (or ovariectomy) is the surgical removal of an ovary or ovariesduring pre-menopause stage can reduse the risk
    7.Nulliparity. The condition of being nulliparous, or not bearing offspring.it is a risk factor
    8.Family History with the disorder can increase risk
    9.Diet like Soya and phyto oestrogens are protective
    10.Saturated fat,red meat,alcohol are dangerous
    11.Increased in higher social economic classes
    for other and more information regarding this matter read in the link below

  2. INTRODUCTION
    Breast cancer is a leading cause of death among women. As of today little is known about the prevention of breast cancer. Therefore, much rests on early detection, when the cancer can be cured completely.
    An ideal screening test should detect cancer or the pre-cancerous condition at a stage when treatment can affect outcome. The rate of false positive and negative results should be low. The test should not cause morbidity, should be reproducible, inexpensive, and suitable for large sections of the population. The best test would be the one that detects abnormal cells before they turn malignant.
    Mammography has long been used as a screening test for breast cancer. It involves taking an X-ray of the breast. It is widely accepted that screening mammography leads to early detection of breast cancer. Recently, however, questions have been raised over whether such early detection actually translates into greater survival.

    LIMITATIONS OF MAMMOGRAPHY
    Since mammography cannot separate normal gland tissue from tumours, it is more effective when gland tissue diminishes with age. Many women retain glandular tissue even as they mature and this camouflages tumours until they are large. Young women have more glandular tissue, which interferes with detection of small cancers.

    BENEFITS OF MAMMOGRAPHY
    Apart from early detection of breast cancer, there are other potential benefits of mammography screening. Although the amount of dense parenchymal tissue can affect the validity of cancer screening, it is also a marker of breast cancer risk. It has been found in a case control study that women with extremely dense breast tissue are at an elevated risk of developing breast cancer than those with extremely fatty breast tissue. The knowledge that breast density is a marker of breast cancer risk can be used to minimise the risk.

    EFFECT ON INCIDENCE OF SURGERY
    Incidence of surgery – tumorectomy and mastectomy – has increased dramatically since the beginning of clinical use of mammography. Screening identifies some slow growing tumours that are not likely to grow bigger in the woman’s remaining lifetime. These can be followed by mammography or treated aggressively, thus increasing the incidence of surgery.
    Improvement in mammography has resulted in the test’s ability to detect a higher number of Ductal Carcinoma in Situ (DCIS). Currently, most of the DCIS are diagnosed by mammography, since there is usually no lump that can be detected by touch. These may not always develop into invasive cancer, but since these lesions are often diffuse, women are treated with bilateral mastectomy.

    STUDIES TO DEMONSTRATE EFFECT ON SURVIVAL
    Critics of the test say that mammography is an imperfect screening test, as it does not detect lesions before they turn cancerous.
    The Canadian National Breast Cancer Screening Study found that annual mammograms combined with physical breast examination did not reduce breast cancer deaths compared to physical examination alone in women aged between 50 and 59. The results reflected a median 13 years of follow up in nearly 40,000 women. Study authors stated that annual physical examination by an expert was a valid option for breast cancer screening, especially where access to mammography was limited.
    Peter Gotzche and Ole Olsen reviewed eight mammography trials in the US, Canada, Scotland and Sweden. They reported that screening for breast cancer with mammography was unjustified. They found the quality of most trials poor. The best trials, they claimed, did not provide evidence of a reduction in either total or breast cancer mortality. Data showed that for every thousand women screened biennially throughout 12 years, one breast cancer death was avoided whereas the total number of deaths increased by six.

    NEW FINDINGS
    However, the latest review of the Swedish trials has found reliable evidence of substantial reduction in fatality. According to this review, Olsen and Gotzche did not address the case fatality benefit of screening-associated early intervention. (This, if it exists, becomes apparent only after a delay of several years.) Screening in elder women seemed to have led to a 55 percent reduction in case-fatality rate and thereby, after requisite delay, in cause-specific mortality.
    Recently, Nystrom and colleagues presented data for over 15 years from four randomised Swedish trials of screening mammography. Despite the reduction in breast cancer mortality, overall mortality showed a relative risk of just 0.98 between the invited and control groups.
    Recently, WHO’s International Agency for Research on Cancer (IARC) convened a working group. The group concluded that in women aged between 50 and 69, mammography reduced the chances of dying from breast cancer by about 35 percent. In younger women there was only a slight benefit.

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